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Xanthurenic acid, the major downstream metabolite of 3-HK capable of crossing the BBB, exhibits both antioxidant and pro-oxidant properties depending on experimental context [158, 161,162,163]

To view a copy of this licence, visit About this article Cite this article Tang, Z., Ye, F., Ni, N

Overall, behavioral recovery, with and without standard treatment, is very poor, which reinforces the need for a new treatment protocol for PNIs

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A separate human trial found that topical GHK-Cu produced collagen increases in 70% of the women treated outperforming both vitamin C and retinoic acid